חדשות המחקר
Michael Edelstein, Haneen Shibli, Jacob Bornstein: Differences in knowledge, attitudes and intentions towards HPV vaccination among young adults from diverse socio-cultural groups in Israel: A cross-sectional study (Vaccine . )
In Israel, The Human Papilloma Virus (HPV) vaccine is recommended to both genders up to age 26. Many 18-26 olds missed their opportunity for vaccination during school. Our study described HPV knowledge, attitudes and vaccination intentions among unvaccinated 18-26 Israeli adults across various demographics, aiming to inform future catch-up vaccination strategies.
Inshirah Sgayer, Muhammad Zidan, Yara Nakhleh Francis, Raneen Abu Shqara, Daniel Glikman, Lior Lowenstein, Maya Frank Wolf: Maternal Colonization of Extended-Spectrum-Beta-Lactamase-Producing Enterobacteriaceae in Preterm Rupture of Membranes (J Obstet Gy
Maternal colonization by Enterobacteriaceae that produce extended-spectrum β-lactamases (ESBL-E) has risen, and the antimicrobial resistance of ESBL-E is significant. We aimed to evaluate the rates of ESBL-E colonization among women with preterm premature rupture of membranes (PPROM) and of maternal-neonatal vertical transmission. We also aimed to compare obstetrical and neonatal complications among ESBL-E positive versus negative maternal colonization in pregnancies complicated by PPROM.
Adi Shani, Nimrod Rahamimov: Research Article: The prediction of the analgesic placebo response is moderated by outward-focused attention: a sham, randomized clinical trial of chronic back pain patients (J Pain .)
The within-subject variability (WSV) of pain-intensity reports has gained attention as a predictor of the placebo response but has demonstrated mixed results. We hypothesized that participants' inward- and outward-directed attention will moderate WSV's prediction of the analgesic placebo response.
Sondra Turjeman: Social, environmental, and developmental factors affect the microbiota of barn owls (Tyto alba) in a cross-fostering experiment (Anim Microbiome . )
Species host diverse microbial communities that can impact their digestion and health, which has led to much interest in understanding the factors that influence their microbiota. We studied the developmental, environmental, and social factors that influence the microbiota of nestling barn owls (Tyto alba) through a partial cross-fostering experiment that manipulated the social and nest environment of the nestlings.
Daniel Bahir, Shirin Hamed Azzam: Thyroid Eye Disease and Artificial Intelligence: A Comparative Study of ChatGPT-3.5, ChatGPT-4o, and Gemini in Patient Information Delivery (Ophthalmic Plast Reconstr Surg . )
This study aimed to compare the effectiveness of 3 artificial intelligence language models-GPT-3.5, GPT-4o, and Gemini, in delivering patient-centered information about thyroid eye disease (TED).
Avi Peretz, Maya Azrad: Diagnosing gastrointestinal infections based on cycle threshold cut-offs of PCR (Microbiol Spectr .)
This study compared the performance of molecular vs stool culture assays for gastrointestinal infection (GII) detection, with focus on defining cycle threshold (Ct) cut-off values for positive culture results.
Avi Benov: Characteristics and survival of hospitalized combat casualties during two major conflicts between Israel and Hamas: 2023 versus 2014 (BMC Emerg Med .)
In the complex landscape of modern warfare, understanding combat-related injuries leading to hospitalization is crucial for optimizing injury treatment. This study aims to compare combat casualty characteristics and outcomes during the major conflicts between Israel and Hamas in 2023 and 2014 as a basis for understanding the effectiveness of trauma care practices for wounded soldiers.
Liron Leibovitch: Direct Anterior vs. Posterior Approach in Simultaneous Bilateral Total Hip Arthroplasty: A Meta-Analysis (Cureus .)
Simultaneous bilateral total hip arthroplasty (SimBTHA) offers benefits such as reduced hospital stay and costs for patients with bilateral hip disease. However, the optimal surgical approach remains uncertain. This study aimed to compare the perioperative outcomes of SimBTHA performed via the direct anterior approach (DAA) versus the posterior approach (PA).
Nofar Mizrachi, Tobias Kube, Liron Rozenkrantz: Perceiving immunity, predicting somatic symptoms: Validation of the 'Perceived Immunity' scale and its association with daily health (Br J Health Psychol . )
While ample research links health beliefs to physical health in both healthy and clinical populations, the specific health beliefs that drive this effect remain underexplored. Addressing this gap is critical for mechanistic examinations and targeted intervention development. Building on previous work, this study aimed to assess subjective beliefs about immune system efficacy and develop a novel Perceived Immunity scale.
Liron Leibovitch: Direct anterior vs other surgical approaches in patients with lumbar stiffness undergoing total hip arthroplasty: a systematic review and meta-analysis (Arch Orthop Trauma Surg .)
The effectiveness of the direct anterior approach (DAA) compared to other surgical approaches for total hip arthroplasty (THA) in patients with lumbar spine stiffness remains unclear. This systematic review and meta-analysis aimed to compare clinical outcomes, including dislocation rates and other complications, between DAA and other surgical approaches for THA in patients with lumbar spine stiffness.
Dylan DSouza, Olawumi Giwa, Milana Frenkel-Morgenstern: ChiTaRS 8.0: the comprehensive database of chimeric transcripts and RNA-seq data with applications in liquid biopsy (Nucleic Acids Res . )
This updated database provides unique information on 1055 chimeric breakpoints derived from public datasets using chromosome conformation capture techniques (the Hi-C datasets). It also includes an expanded list of gene fusions that are potential drug targets, and chimeric breakpoints across 934 cell lines, positioning ChiTaRS 8.0 as a valuable resource for testing personalized cancer therapies.
Sagi Hamo, Lee S Izhaki-Tavor, Moshe Dessau: The RNA Silencing Suppressor P8 From High Plains Wheat Mosaic Virus is a Functional Tetramer (J Mol Biol .)
In plants, RNA interference (RNAi) serves as a critical defense mechanism against viral infections by regulating gene expression. However, viruses have developed RNA silencing suppressor (RSS) proteins to evade this defense mechanism....Our study focuses on P8, an RSS protein from HPWMoV. Understanding its structure and assembly is a crucial step toward comprehending how these viruses counteract host defenses, aiding in combatting malnutrition.
Khalaf Kridin: Mortality in adult patients with chronic spontaneous urticaria: A real world cohort study (J Allergy Clin Immunol . )
Chronic spontaneous urticaria (CSU), a common and debilitating disease, is widely held not to be life-limiting, but the mortality of CSU has not been investigated. Objective: To assess all-cause mortality in CSU patients, risk for comorbidities that are leading causes of death and impact of guideline-recommended urticaria treatments on mortality rates.
Omry Koren: Antibiotic-perturbed microbiota and the role of probiotics (Nat Rev Gastroenterol Hepatol .)
The disruptive effect of antibiotics on the composition and function of the human microbiota is well established. However, the hypothesis that probiotics can help restore the antibiotic-disrupted microbiota has been advanced, with little consideration of the strength of evidence supporting it.
Avi Benov, Elon Glassberg: The Turkish Earthquake: Adapting a Relevant Medical Relief Response Mode ( Disaster Med Public Health Prep .)
On February 6, 2023, a Mw 7.8 earthquake struck southern and central Turkey and northern and western Syria..... the State of Israel dispatched 2 missions, with the first on the ground the same day as the earthquake. Under guidance of the local health authorities, it was determined that the most effective approach would be to support an existing medical facility rather than establishing a standalone field operation....