חדשות המחקר
Khalaf Kridin: Psoriasis and Renal Disorders: A Large-Scale Population-Based Study in Children and Adults (Dermatology .)
Psoriasis is a systemic disease with associated comorbidities. An association between renal diseases and psoriasis has previously been reported in adult patients, but little is known about renal diseases in pediatric patients. This study determines whether there is an association between psoriasis and renal comorbidities in adult and pediatric patients.
Michael Edelstein: Characteristics associated with COVID-19 vaccine uptake among adults aged 50 years and above in England (8 December 2020-17 May 2021): a population-level observational study (BMJ Open . )
To determine characteristics associated with COVID-19 vaccine coverage among individuals aged 50 years and above in England since the beginning of the programme
Enav Yefet: An informative video before planned Cesarean-delivery and maternal anxiety-a multicenter randomized controlled trial (Am J Obstet Gynecol MFM .)
Cesarean delivery (CD) is one of the most common procedures performed in obstetrics, and although CD is a blissful occasion, it is commonly associated with fear and anxiety for the new mother. We aimed to study the impact of watching a detailed, informative video on maternal anxiety levels, childbirth experience, and patient satisfaction - in patients undergoing a primary CD.
Moriah Shachar: Profile Trends of Non-COVID Patients Admitted to the Cardiac Intensive Care Unit during the 2020 COVID Pandemic (Am J Med Sci .)
During the COVID-19 outbreak, numerous reports indicated a higher mortality rate among cardiovascular patients. We investigated how this trend applied to patients admitted to the cardiac intensive care unit (CICU).
Chaim Putterman; High incidence of proliferative and membranous nephritis in SLE patients with low proteinuria in the Accelerating Medicines Partnership (Rheumatology (Oxford) . )
Delayed detection of lupus nephritis associates with worse outcomes. There are conflicting recommendations regarding a threshold level of proteinuria at which biopsy will likely yield actionable management. This study addressed the association of urine protein creatinine ratios (UPCR) with clinical characteristics and investigated the incidence of proliferative and membranous histology in patients with a UPCR between 0.5 and 1.
Jacob Bornstein: Inauguration Editorial (J Low Genit Tract Dis . )
Inauguration Editorial from new editor in chief.
Lior Lowenstein: The efficacy and safety of a single maintenance laser treatment for stress urinary incontinence: a double-blinded randomized controlled trial (Int Urogynecol J .)
Evaluates the efficacy and safety of a single carbon dioxide (CO2) laser maintenance treatment in women previously treated successfully with laser for stress urinary incontinence (SUI), who have demonstrated a decline in treatment effect.
Miriam Ethel Bentwich, Nehora Amar-Gavrilman: To debate or not to debate? Examining the contribution of debating when studying medical ethics in small groups (BMC Med Educ .)
Medical ethics is a significant learning topic for medical students, and often studied through small group learning (SGL) to encourage critical thinking (CT) and tolerance for ambiguity, both considered particularly important when coping with medical ethics dilemmas. However, a previous study about CT and tolerance for ambiguity in medical ethics SGL produced mixed results. Debating is a pedagogical tool known to enhance CT but never used before in medical ethics learning. This paper examines whether the use of debate may enhance medical ethics SGL by contributing to the CT of students and their tolerance of ambiguity.
Tawfik Khoury, Amir Mari: The impact of ethnicity on chronic hepatitis B infection course and outcome: big data analysis from Israel (Ethn Health .)
The effect of ethnicity on chronic hepatitis B virus (CHB) infection's course and outcome has attracted little research. We aimed to compare different aspects of ethnic disparities in CHB patients, including prevalence, phenotypes, management, and outcome between two major ethnic groups in Israel.
Naaem Simaan: Characteristics of Cerebral Sinus Venous Thrombosis Patients Presenting with Intracerebral Hemorrhage (J Clin Med . )
Patients with cerebral venous sinus thrombosis (CVST) occasionally present with intracerebral hemorrhage (ICH). In this study, we aimed to identify predictors for ICH in CVST patients.
Maya Frank Wolf, Maayan Ben-Nun, Inshirah Sgayer, Oleg Shnaider, Alaa Aiob, Marwan Odeh, Jacob Bornstein: The association between acute lower abdominal pain over a previous caesarean scar and uterine rupture (J Obstet Gynaecol .)
Pregnant women with previous caesarean delivery might suffer from acute lower abdominal pain located at the site of previous caesarean scar (CS). The association between this complaint and uterine rupture (UR) is not fully understood. Therefore, we aimed to examine the risk of UR in women with acute persistent abdominal pain (APAP) over a previous CS and to investigate all the women with UR, with or without APAP and with or without previous CS, in order to determine risk factors, clinical presentation and management.
Michael Edelstein: Providing early indication of regional anomalies in COVID-19 case counts in England using search engine queries (Sci Rep .)
Prior work has shown the utility of using Internet searches to track the incidence of different respiratory illnesses. Similarly, people who suffer from COVID-19 may query for their symptoms prior to accessing the medical system (or in lieu of it). To assist in the UK government's response to the COVID-19 pandemic we analyzed searches for relevant symptoms on the Bing web search engine from users in England to identify areas of the country where unexpected rises in relevant symptom searches occurred.
Irith Weissman, Efrat Shuster Biton, Limor Kalfon, Ayalla Fedida, Elite Arnon-Sheleg, Tzipora C Falik Zaccai: A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness (J Am Soc Nephrol .)
The endocytic reabsorption of proteins in the proximal tubule requires a complex machinery and defects can lead to tubular proteinuria. The precise mechanisms of endocytosis and processing of receptors and cargo are incompletely understood. EHD1 belongs to a family of proteins presumably involved in the scission of intracellular vesicles and in ciliogenesis. However, the relevance of EHD1 in human tissues, in particular in the kidney, was unknown.
Jacob Bornstein, Eilam Palzur: Vulvodynia: a neuroinflammatory pain syndrome originating in pelvic visceral nerve plexuses due to mechanical factors (Arch Gynecol Obstet .)
This short opinion aimed to present the evidence to support our hypothesis that vulvodynia is a neuroinflammatory pain syndrome originating in the pelvic visceral nerve plexuses caused by the failure of weakened uterosacral ligaments (USLs) to support the pelvic visceral nerve plexuses, i.e., T11-L2 sympathetic and S2-4 parasympathetic plexuses.