חדשות המחקר
Tal Zadok, Otzem Chasid: Comparison of Biometry Measurements and Intraocular Lens Power Prediction Between Two Swept-source Based OCT Biometers (J Cataract Refract Surg .)
Evaluates the agreement in biometry measurements and intraocular lens (IOL) power prediction between the Eyestar 900 and the IOLMaster 700.
Hannan Rohana, Anat Hager-Cohen, Maya Azrad, Avi Peretz: Trend of Changes in Chloramphenicol Resistance during the Years 2017-2020: A Retrospective Report from Israel (Antibiotics (Basel) .)
Resistant bacteria limit treatment options. This challenge has awakened interest in antibiotics that are no longer in use due to side effects, such as chloramphenicol. This work investigated trends in chloramphenicol resistance rates during 2017-2020 in bacteria isolated from diverse clinical samples at the Baruch Padeh Medical Center, Poriya, Israel.
Ibrahim Marai, Rabea Haddad, Nizar Andria, Wadi Kinany, Yevgeni Hazanov , Bruce M Kleinberg, Edo Birati, Shemy Carasso: Left Ventricular "Longitudinal Rotation" and Conduction Abnormalities-A New Outlook on Dyssynchrony (J Clin Med . )
The complete left bundle branch block (CLBBB) results in ventricular dyssynchrony and a reduction in systolic and diastolic efficiency. We noticed a distinct clockwise rotation of the left ventricle (LV) in patients with CLBBB ("longitudinal rotation"). The aim of this study was to quantify the "longitudinal rotation" of the LV in patients with CLBBB in comparison to patients with normal conduction or complete right bundle branch block (CRBBB).
Khalaf Kridin, Ralf J Ludwig: Risk of infections in patients with pemphigus treated with rituximab versus azathioprine or mycophenolate mofetil: A large-scale global cohort study (Br J Dermatol . )
he risk of infectious complications among patients with pemphigus managed by rituximab is yet to be precisely elucidated. Objective: To evaluate the risk of infections in patients with pemphigus managed by rituximab versus first-line corticosteroid-sparing agents (azathioprine and mycophenolate mofetil [MMF]).
Anthony Riches, Menahem Neuman, Jacob Bornstein: The Light-weight Mid-urethral Sling Implant for Female Stress Urinary Incontinence Treatment: A One-Year Postoperative Follow-up Study (Isr Med Assoc J .)
Serasis® (Serag-Wiessner KG, Naila, Germany) is a light-weight mid-urethral sling for treating stress urinary incontinence (SUI). Its insertion is considered less traumatic than other mid-urethral slings. Objectives: To define postoperative outcomes following Serasis implantation. To compare the efficacy and complication rates of the implant to those of other common techniques.
Tali Butler: Pediatric psychiatric emergency rooms during COVID-19: a multi-center study (BMC Psychiatry .)
The COVID-19 (SARS-CoV-2) pandemic has been a major stressor for the mental health and well-being of children and adolescents. Surveys and reports from hotlines indicate a significant rise in mental health problems. As the psychiatric emergency room (ER) is a first-line free-of-charge facility for psychiatric emergencies, we expected to see a significant increase in visits, specifically of new patients suffering from anxiety, depression, or stress-related disorders.
CORRECTION/ERRATUM HERE: https://pubmed.ncbi.nlm.nih.gov/36703106/
Edo Y Birati: Left Ventricular Assist Devices: A Primer For the General Cardiologist (J Am Heart Assoc .)
Durable implantable left ventricular assist devices (LVADs) have been shown to improve survival and quality of life for patients with stage D heart failure. Even though LVADs remain underused overall, the number of patients with heart failure supported with LVADs is steadily increasing. Therefore, general cardiologists will increasingly encounter these patients. In this review, we provide an overview of the field of durable LVADs.
Hanna Mandel, Tzipora C Falik-Zaccai: Genetic defects in peroxisome morphogenesis (Pex11β, dynamin-like protein 1, and nucleoside diphosphate kinase 3) affect docosahexaenoic acid-phospholipid metabolism (J Inherit Metab Dis .)
Peroxisomes are essential organelles involved in lipid metabolisms including plasmalogen biosynthesis and β-oxidation of very long-chain fatty acids. Peroxisomes proliferate by the growth and division of pre-existing peroxisomes. The peroxisomal membrane is elongated by Pex11β and then divided by the dynamin-like GTPase, DLP1 (also known as DRP1 encoded by DNM1L gene), which also functions as a fission factor for mitochondria. Nucleoside diphosphate kinase 3 (NME3) localized in both peroxisomes and mitochondria generates GTP for DLP1 activity. Deficiencies of either of these factors induce abnormal morphology of peroxisomes and/or mitochondria, and are associated with central nervous system dysfunction. To investigate whether the impaired division of peroxisomes affects lipid metabolisms, we assessed the phospholipid composition of cells lacking each of the different division factors.
Third trimester re-screening for gestational diabetes in morbidly obese women despite earlier negative test can reveal risks for obstetrical complications (J Obstet Gynaecol Res . )
We investigated associations of maternal obesity with late gestational diabetes mellitus (GDM) diagnosis (>34 weeks) in women with previous normal glucose screening, and associations of late GDM with obstetrical outcomes.
Raneen Abu Shqara, Shany Or, Yara Nakhleh Francis, Lior Lowenstein, Maya Frank Wolf
Shams Twafra , Tal Sneh, Kolluru D Srikanth, Tomer Meirson, Alessandro Genna, Hava Gil-Henn: Correction: A novel Pyk2-derived peptide inhibits invadopodia-mediated breast cancer metastasis (Oncogene . )
Erratum for A novel Pyk2-derived peptide inhibits invadopodia-mediated breast cancer metastasis. Twafra S, Sokolik CG, Sneh T, Srikanth KD, Meirson T, Genna A, Chill JH, Gil-Henn H.
Khalaf Kridin: Management and treatment outcome of DRESS patients in Europe: an international multicentre retrospective study of 141 cases (J Eur Acad Dermatol Venereol . )
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare but potentially fatal drug hypersensitivity reaction. Objective: To explore treatment approaches across Europe and their impact on the disease course, as well as prognostic factors and culprit drugs.
Jacob Bornstein: High-risk HPV testing vs liquid-based cytology for cervical cancer screening among 25- to 30-year-old women: A historical cohort study (Acta Obstet Gynecol Scand .)
High-risk human papilloma virus (hrHPV) DNA testing is more sensitive than cytology screening, achieving greater protection against cervical cancer. Controversy exists regarding the preferred screening method for women 25-30 years of age. At this age, infection with HPV is common and usually transient. Consequently, hrHPV screening in this age group is fraught with high false-positive screening results, leading to more colposcopies and unnecessary treatments with the potential for harm. In the present study, we aimed to compare the results of two screening methods in relation to high-grade cervical intraepithelial lesion detection rate in the young age group of 25-30 years.
Michael Rechter, Sivan Saraph, Hector Cohen, Ohad Ronen: Nondiagnostic Test Result Rates Following Thyroid Extra-Fine-Needle Aspiration (Am J Clin Pathol. )
The first Bethesda classification category of thyroid fine-needle aspiration biopsy (FNAB) is nondiagnostic (ND), which indicates that the specimen's cellularity is inadequate for evaluation. This work investigated the effect of needle diameter size on ND rates by comparing diagnostic outcomes of FNAB samples collected with 23-, 25-, and 27-gauge needles.
Raneen Abu Shqara, Shay Bussidan, Daniel Glikman, Hagai Rechnitzer, Lior Lowenstein, Maya Frank Wolf: Clinical implications of uterine cultures obtained during urgent caesarean section (Aust N Z J Obstet Gynaecol . )
Postpartum endometritis (PPE) is 12-25 times more common following caesarean sections (CS) performed after labour onset than after vaginal delivery. Risk factors for PPE include prolonged rupture of membranes (ROM), chorioamnionitis, prolonged labour, multiple cervical examinations and Group B Streptococcus colonisation of the lower genital tract. Aims: We compared uterine culture results and microbial antibiotic susceptibility according to ROM duration in emergent intrapartum CS. Secondary outcomes included PPE incidence, and identification of clinical and microbiological predictors of infectious postpartum morbidity.