Moshe Matan, Avi Peretz, Meital Gal-Tanamy: Altered somatic hypermutation patterns in COVID-19 patients classifies disease severity (Front Immunol . )

The success of the human body in fighting SARS-CoV2 infection relies on lymphocytes and their antigen receptors. Identifying and characterizing clinically relevant receptors is of utmost importance. Methods: We report here the application of a machine learning approach, utilizing B cell receptor repertoire sequencing data from severely and mildly infected individuals with SARS-CoV2 compared with uninfected controls.