Recent Publications
A. Mari, M. Mahamid, H. Amara: Chronic Constipation in the Elderly Patient: Updates in Evaluation and Management (Korean J Fam Med.)
Chronic constipation (CC) is a common disorder in the elderly population globally and is associated with comorbidities and negative implications on the quality of life... This review aimed to summarize the most updated knowledge for primary care physicians in the approach and management of CC in elderly patients.
Amir Mari: Eosinophilic Esophagitis in Adults: A Concise Overview of an Evolving Disease (Korean J Fam Med.)
This article provides an overview of the current knowledge base regarding eosinophilic esophagitis (EoE) including epidemiology, genetics, pathogenesis, common clinical presentations, the interplay between EoE and GERD, diagnostic approaches, and therapeutic options available to the PCP.
N. Tsabar, Y. Grossman, S. Eilat-Tsanani: Randomized trial results of alerting primary clinicians to severe weight loss among older adults in the Low Indexes of Metabolism Intervention Trial part A (Geriatr Gerontol Int.)
Tests whether alerting clinicians to severe weight loss in older patients leads to higher dietitian visit rates, to higher body mass index (BMI) levels and, mainly, to lower annual death risk
Tal Shachar: The impact of helicopter emergency medical service on acute ischemic stroke patients: A systematic review (Am J Emerg Med.)
Helicopter emergency medical services (HEMS) is commonly elected transport for acute ischemic stroke (AIS) known as a time-critical illness. This study conducted a systematic review in order to explore the HEMS impact on healthcare status, process and outcome measures for AIS patients.
Jacob Bornstein: The International Classification of Diseases, 11th Revision: A Step-Back for Women With Vulvodynia? (J Low Genit Tract Dis.)
The aim of the study was to compare the International Classification of Diseases, 11th revision, (ICD-11) with current terminology of vulvodynia, approved by a broad-based consensus of the International Society for the Study of Vulvovaginal Disease (ISSVD), the International Society for the Study of Women Sexual Health (ISSWSH), and the International Pelvic Pain Society (IPPS).
Abraham O. Samson , Baruh Polis: Norvaline Reduces Blood Pressure and Induces Diuresis in Rats with Inherited Stress-Induced Arterial Hypertension (Biomed Res Int.)
The data indicate that L-norvaline is a potential antihypertensive agent and deserves to be clinically investigated.
RA Dar , AD Amiel, S Srouji: Trans-implant treatment of chronic recurrent maxillary sinusitis via dynamic implants with an internal port: Experience with 31 cases (Int J Oral Maxillofac Surg.)
This study was performed to test a protocol for trans-implant treatment of chronic recurrent maxillary sinusitis (CRS), via implants with an internal removable sealing screw. The appropriate indications for treatment, optimal number of treatment sessions, and general schedule of treatment and follow-up were assessed.
Lital Ozeri, Omry Koren: Nicotianamine-chelated iron positively affects iron status, intestinal morphology and microbial populations in vivo (Gallus gallus) (Sci Rep.)
This study explored the effects of iron fortified wheat on gastrointestinal health.
Arginase Inhibition Supports Survival and Differentiation of Neuronal Precursors in Adult Alzheimer's Disease Mice (Int J Mol Sci.)
Previous results indicated a potential effect of arginase inhibition, with norvaline, on various aspects of neurogenesis in triple-transgenic mice. To better evaluate this effect, the researchers chronically administered an arginase inhibitor, norvaline, to triple-transgenic and wild-type mice, and applied an advanced immunohistochemistry approach with several biomarkers and bright-field microscopy. (B. Polis, KD Srikanth, V. Gurevich, N. Bloch, H. Gil-Henn, AO Samson)
Forsan Jahshan, Eyal Sela, Maayan Gruber: Pneumothorax and Pneumomediastinum Complicating Pediatric Foreign Body Aspiration (Ear Nose Throat J)
Pneumothorax (PNT) and pneumomediastinum (PMT) induced by foreign body (FB) aspiration in children is a rare but potentially life-threatening event. This situation may not be diagnosed in time due to its rarity and atypical presentation in some cases. Accurate and timely diagnosis is essential in order to provide adequate treatment and avoid long-term morbidity.
Zaher Armaly: Glycocalyx degradation in ischemia-reperfusion injury (Am J Pathol.)
The glycocalyx is a layer coating the luminal surface of vascular endothelial cells. It is vital for endothelial function as it participates in microvascular reactivity, endothelium interaction with blood constituents, and vascular permeability. Structural and functional damage to glycocalyx occurs in various disease states....This review focuses on alterations of glycocalyx during I/R injury in general and to vital organs in particular, and on maneuvers aimed at glycocalyx recovery during I/R injury.
Irina Nordkin, Alexander Goldberg, Zeev Israeli, Majdi Halabi: Complicated acute myocardial infarction with simultaneous occlusion of two coronary arteries (Clin Case Rep)
Simultaneous occlusion of two coronary arteries in acute MI is infrequent and may be accompanied by cardiogenic shock. Prompt restoration of normal coronary flow can salvage the myocardium and decrease a possible risk of death from complications.
Avi Benov, Elon Glassberg: The effects of military-wide introduction of advanced tourniquets in the Israel Defense Forces (Injury)
This study aimed to assess the effects of the wide introduction of advanced tourniquets on the rate of tourniquet applications, the type of tourniquet applied, and the differences in hospitalisation outcomes following the introduction.
Following the IDF military-wide introduction of advanced tourniquets, the tourniquet application rate rose sharply, the use of old tourniquets ceased over time, and in-hospital amputation rate did not increase. These findings suggest that the awareness for haemorrhage control using advanced tourniquets rose.
Milana Frenkel-Morgenstern: Current perspectives on circulating tumor DNA, precision medicine, and personalized clinical management of cancer (Mol Cancer Res)
Circulating tumor DNA (ctDNA) has recently emerged as a minimally invasive 'liquid biopsy' tool in precision medicine. This review presents current evidence on the potential role for ctDNA in helping to guide individualized clinical treatment decisions for patients with melanoma, castration-resistant prostate cancer, breast cancer, metastatic colorectal cancer, and non-small cell lung cancer.
Andrei Braester: Morbid obesity and mortality in patients with venous thromboembolism. Findings from real life clinical practice (Chest.)
The influence of morbid obesity on mortality in patients receiving anticoagulant therapy for venous thromboembolism (VTE) has not been consistently evaluated.
In patients with VTE, the risk for death during anticoagulation was about one third lower in morbidly obese patients than in those with normal weight, independently of the presence of cancer.