Recent Publications
Orly Yakir, Jacob Bornstein: Is There a Place for the Introduction of Colposcopy Quality Standards? (J Low Genit Tract Dis .)
The aims of the study were to examine the degree of compliance with international quality measures for colposcopy in Israel, which does not currently have formal guidelines and to compare the achievement of quality measures between clinical settings.
Adi Eshel, Amir A Kuperman, Radi Shahien, Omry Koren: Patterns of Salivary Microbiota Injury and Oral Mucositis in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation (Blood Adv.)
Oral mucositis (OM) is a common debilitating dose-limiting toxicity of cancer treatment, including hematopoietic stem cell transplantation (HSCT). We hypothesized that the oral microbiome is disturbed during allogeneic HSCT, partially accounting for the variability in OM severity.
Menachem Alcalay: Validation of the Wexner Scale in a Hebrew-speaking Population (Int Urogynecol J.)
The Cleveland Clinic Incontinence Score, known as the Wexner Score (WS), is a simple, disease-specific questionnaire for anal incontinence (AI) assessment. We aimed to translate and validate a Hebrew version of the WS.
Sivan Spitzer-Shohat: Health Equity and COVID-19: Global Perspectives (Int J Equity Health.)
The COVID-19 is disproportionally affecting the poor, minorities and a broad range of vulnerable populations, due to its inequitable spread in areas of dense population and limited mitigation capacity due to high prevalence of chronic conditions or poor access to high quality public health and medical care. Moreover, the collateral effects of the pandemic due to the global economic downturn, and social isolation and movement restriction measures, are unequally affecting those in the lowest power strata of societies. To address the challenges to health equity and describe some of the approaches taken by governments and local organizations, we have compiled 13 country case studies from various regions around the world.
Dana Binyamin, Omry Koren: Sex Dependent Effects of Post-Natal Penicillin on Brain, Behavior and Immune Regulation Are Prevented by Concurrent Probiotic Treatment (Sci Rep . )
There is increasing awareness of the need to consider potential long-term effects of antibiotics on the health of children. In addition to being associated with immune and metabolic diseases, there is evidence that early-life antibiotic exposure can affect neurodevelopment. Here we investigated the effect of low dose of penicillin V on mice when administered for 1 week immediately prior to weaning.
Moshe Ben Ami, Yasmin Bssam Abbas, Naama Marcus: The Impact of a Nationwide Hands-On Workshop on the Diagnostic Rates and Management of Obstetrical Anal Sphincter Injuries (OASI) In Israel (Colorectal Dis .)
Evaluates the influence of a half day, hands-on, workshop on detection and repair of Obstetric Anal Sphincter Injuries (OASI).
Nimer Assy: A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial of MHAA4549A, a Monoclonal Antibody, plus Oseltamivir in Patients Hospitalized with Severe Influenza A Virus Infection (Antimicrob Agents Chemother .)
For patients hospitalized with severe influenza A virus infection, morbidity and mortality remain high. MHAA4549A, a human monoclonal antibody targeting the influenza A virus hemagglutinin stalk, has demonstrated pharmacological activity in animal studies and in a human influenza A challenge study. We evaluated the safety and efficacy of MHAA4549A plus oseltamivir against influenza A virus infection in hospitalized patients.
Guy Rozen, Ibrahim Marai, Nizar Andria, Shemy Carasso, Diab Ghanim, Offer Amir: Utilization and Complications of Catheter Ablation for Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy (J Am Heart Assoc.)
Atrial fibrillation (AF) is common and bears a major clinical impact in patients with hypertrophic cardiomyopathy (HCM). We aimed to investigate the use and real-world safety of catheter ablation for AF in patients with HCM.
Tomer Meirson: Safety of BRAF+MEK Inhibitor Combinations: Severe Adverse Event Evaluation (Cancers (Basel) . )
The selective BRAF and MEK inhibitors (BRAFi+MEKi) have substantially improved the survival of melanoma patients with BRAF V600 mutations. However, BRAFi+MEKi can also cause severe or fatal outcomes. We aimed to identify and compare serious adverse events (sAEs) that are significantly associated with BRAFi+MEKi.
Baruh Polis: Striatal Cholinergic Interneurons Exert Inhibition on Competing Default Behaviors Controlled by the Nucleus Accumbens and Dorsolateral Striatum (Eur J Neurosci.)
With repeated practice, learned actions become more skilled, and eventually highly stereotypical. This transition is accompanied by a shift in striatal control over behavior from ventral and dorsomedial striatum to dorsolateral striatum. The cholinergic interneurons (CINs) in the striatum are central to striatal computation. Yet, their role in the transition from motivated to stereotypic behavior is still unclear. In this study we examined whether CINs contribute to the competition between both control systems.
Noa Abrahami, Ido Izhaki, Johnny S Younisa: Is there a difference in ovarian reserve biomarkers and ovarian response between the right and left ovaries? (Reprod Biomed Online .)
Is there a difference in ovarian reserve biomarkers and ovarian response between the right and left ovaries of infertile women undergoing IVF treatments?
Arik David, Jacob Bornstein: Evaluation of Long-Term Surgical Success and Satisfaction of Patients After Vestibulectomy (J Low Genit Tract Dis.)
Vestibulectomy is one of the only proven therapeutic treatments for provoked vulvodynia (PVD). However, little is known about long-term surgical success. Patients who underwent vestibulectomy between 1991 and 2003 were interviewed to assess frequency of intercourse and degree of pain during various activities, as well as satisfaction with and willingness to recommend the surgery. We also examined the outcome relation to PVD type being primary or secondary. Differences in pain over time were assessed using a paired-sample t test or a Wilcoxon signed-rank test.
Tamer Jamal, Amjad Shalabi, Liza Grosman-Rimon, Diab Ghanim, Offer Amir, Erez Kachel: Veno-arterial Extracorporeal Membrane Oxygenation for Electrical Injury Induced Cardiogenic Shock Support: A Case Report (J Cardiothorac Surg.)
High voltage electrical injury (HVEI) of more than 1000 V is a potentially devastating form of a multisystem injury associated with high morbidity and mortality. We present the first case of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) as a life saving device for treating a patient with severe cardiogenic shock after a high voltage electrical injury.
