Recent Publications
Mizied Falah: Correlation between cytotoxicity in cancer cells and free radical-scavenging activity: In vitro evaluation of 57 medicinal and edible plant extracts (Oncol Lett)
...the discovery of novel anticancer drugs is urgently required. Nature is considered an important source of the discovery of anticancer treatments, and many of the cytotoxic medicines in clinics today are derived from plants and other natural sources.... The current study reports on the screening of extracts from 57 plants that are used in the galilee district as a food and/or for traditional medicine. Investigating the free radical scavenging capacity and these plants, and their cytotoxicity, may prove helpful to high‑throughput screening projects that use antioxidants and cytotoxic natural products. The current study assessed the correlation between free radical scavenging and cytotoxicity.
Guy Rozen: Safety and In-Hospital Outcomes of Transvenous Lead Extraction for Cardiac Implantable Device-Related Infections: Analysis of 13 Years of Inpatient Data in the United States (JACC Clin Electrophysiol)
The aim of this study was to investigate the safety and in-hospital outcomes of transcutaneous lead extraction (TLE) associated with device-related infection (DRI) in the United States from 2003 to 2015.
Riga Stradins University Trains in Orthopedics, at Ziv/Azrieli Faculty of Medicine
Study course in orthopedics for RSU students was conducted by one of the most prominent traumatologists and orthopedists in treating complicated injuries to the limbs – Professor Alexander Lerner, MD, PhD, Professor at the Azrieli Faculty of Medicine of the Bar-Ilan University, Head of the Orthopedics Department at Ziv Medical Center. See here.
Sophia Eilat-Tsanani: Ten-Year Follow-up of Statin Use Over 65 Years of Age (J Am Geriatr Soc 67:2038-2044,2019)
Adherence to statins may be associated with reduced mortality and cardiovascular morbidity among older adults. See here.
David Azoulay: Prediction of Chemotherapy-Induced Peripheral Neuropathy in Patients with Lymphoma and Myeloma: the Roles of Brain-Derived Neurotropic Factor Protein Levels and A Gene Polymorphism (J Clin Neurol)
Brain-derived neurotrophic factor (BDNF) is a neuronal growth factor that plays an essential role in the maintenance of the nervous system. We have evaluated the peripheral blood protein levels of BDNF and the valine-to-methionine substitution at codon 66 (Val66Met) single-nucleotide polymorphism (SNP) as potential biomarkers for the early recognition of chemotherapy-induced peripheral neuropathy (CIPN) in non-Hodgkin lymphoma and multiple myeloma patients.
David Azoulay: Brain derived neurotropic factor single nucleotide polymorphism Val66Met and serum protein levels are associated with development of vincristine‐induced peripheral neuropathy in patients with lymphoma (BJH)
Vincristine is a chemotherapeutic agent that is associated with chemotherapy‐induced peripheral neuropathy (CIPN) (Legha, 1986), although the reason why some patients are more vulnerable to CIPN than others remains unclear. Our preliminary studies, showing a possible link between CIPN and blood levels of brain‐derived neurotrophic factor (BDNF) (Azoulay et al, 2014), point to BDNF as a potential biomarker for CIPN. The current study explored the effects of serum BDNF and the BDNF‐Val66Met, a single nucleotide polymorphism (SNP) causing deficit in cellular distribution and secretion of BDNF in the neuronal cells (Egan et al, 2003) of patients with non‐Hodgkin lymphoma (NHL) who develop CIPN.
