Recent Publications
Avi Benov: Association between the number of individuals injured in a traumatic event and posttraumatic stress disorder among hospitalized trauma patients (J Trauma Stress . )
Posttraumatic stress disorder (PTSD) often occurs following mass casualty events, yet the connection between the number of individuals injured in an event and PTSD risk in smaller-scale events (i.e., involving one or several injured persons) remains unclear. We conducted a registries-based study cross-referencing three databases across the continuum of care for military trauma patients hospitalized for traumatic injuries.
Naim Shehadeh: Safety, Growth and Development After Dapagliflozin or Saxagliptin in Children With Type 2 Diabetes (T2NOW Follow-Up) (J Clin Endocrinol Metab . )
The T2NOW trial of dapagliflozin or saxagliptin versus placebo in pediatric patients with type 2 diabetes (T2D) demonstrated promising efficacy data for dapagliflozin and did not raise any safety concerns over 52 weeks.
Objective: Assess long-term effects of prior dapagliflozin/saxagliptin administration on safety, growth and development.
Rawi Hazzan: Sex Differences in Colonoscopy Indications and Findings: Results from a Large Multicenter Database (J Womens Health (Larchmt) .)
Sex-based differences are common among diseases. We aimed to investigate the differences in colonoscopy indications and its findings between males and females.
Shirin Hamed Azzam, Salem Kassem, Jerdev Michael: Langerhans cell histiocytosis of the orbit: pediatric case series (Can J Ophthalmol . )
Describes the clinical, imaging characteristics, and treatment of pediatric orbital Langerhans cell histiocytosis (LCH).
Michael Edelstein: Long Covid: a global health issue - a prospective, cohort study set in four continents (BMJ Glob Health .)
A proportion of people develop Long Covid after acute COVID-19, but with most studies concentrated in high-income countries (HICs), the global burden is largely unknown. Our study aims to characterise long-term COVID-19 sequelae in populations globally and compare the prevalence of reported symptoms in HICs and low-income and middle-income countries (LMICs).
Naaem Simaan: Development and Validation of a Clinical Score to Predict Epilepsy After Cerebral Venous Thrombosis (JAMA Neurol .)
One of 10 patients develop epilepsy in the late phase after cerebral venous thrombosis (CVT) diagnosis but predicting the individual risk is difficult.
Objective: To develop and externally validate a prognostic score to estimate the individual risk of post-CVT epilepsy.
Rawi Hazzan: Increased Risk of Non-Hodgkin Lymphoma in Autoimmune Hepatitis: A Large Retrospective Cohort Study (J Clin Med . )
Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease caused by an autoimmune attack on hepatocytes. The first-line treatment for AIH comprises two core components: glucocorticoids and thiopurine analog inhibitors and mycophenolate mofetil (MMF). Numerous studies have suggested an increased risk for lymphoma among patients with either rheumatoid arthritis or inflammatory bowel disease (IBD) who are treated with azathioprine/6-mercaptopurine (6-MP). The relative risk of non-Hodgkin lymphoma (NHL) among autoimmune hepatitis patients treated with these immunosuppressive drugs remains unclear. We aimed at investigating the risk of NHL across a large retrospective AIH cohort after a long-term follow-up.
Yaara Artsi: Advancing Clinical Practice: The Potential of Multimodal Technology in Modern Medicine (J Clin Med .)
Multimodal technology is poised to revolutionize clinical practice by integrating artificial intelligence with traditional diagnostic modalities. This evolution traces its roots from Hippocrates' humoral theory to the use of sophisticated AI-driven platforms that synthesize data across multiple sensory channels. The interplay between historical medical practices and modern technology challenges conventional patient-clinician interactions and redefines diagnostic accuracy. Highlighting applications from neurology to radiology, the potential of multimodal technology emerges, suggesting a future where AI not only supports but enhances human sensory inputs in medical diagnostics. This shift invites the medical community to navigate the ethical, practical, and technological changes reshaping the landscape of clinical medicine.
Basel H Nasser, Jimmy E Jadaon, Nibal Awad-Khamaisy, Luna Abo Lfoul, Israel Hendler: Novel risk factors associated with retained placenta after vaginal birth (Int J Gynaecol Obstet . )
Objective: To evaluate maternal and obstetric risk factors associated with retained placenta following singleton live vaginal births.
Ory Wiesel, Alaa Awad, Lina Abzah: The Potential Benefit of a Novel Urine Biosensor Platform for Lung Cancer Detection in the Decision-Making Process: From the Bench to the Bedside (J Clin Med . )
Lung cancer is the leading cause of cancer-related mortality worldwide. Lung cancer screening and early detection resulted in a decrease in cancer-specific mortality; however, it introduced additional dilemmas and adherence barriers for patients and providers. Methods: Innovations such as biomolecular diagnosis and biosensor-based technology improve the detection and stratification of high-risk patients and might assist in overcoming adherence barriers, hence providing new horizons for better selection of screened populations.
Inshirah Sgayer, Sondos Hassan, Talal Sarhan, Nadine Ashkar, Lior Lowenstein, Maya Frank Wolf: Antenatal corticosteroids for late small-for-gestational-age fetuses (J Perinat Med .)
Compares neonatal morbidity in late preterm pregnancies with small-for-gestational-age fetuses, between those exposed and not exposed to antenatal corticosteroids (ACS).
Chaim Putterman: Soluble urine activated leukocyte cell adhesion molecule is a strong predictor of lupus nephritis (Rheumatology (Oxford) . )
Evaluates urinary activated leucocyte cell adhesion molecule (ALCAM) and CD6 as predictors of lupus nephritis (LN) progression or disease resolution across a 1-year study.
Khalaf Kridin, Rimma Laufer-Britva: Alopecia Areata and malignancies: uncertainties clarified by a large-scale population-based study (Arch Dermatol Res . )
The association of AA with malignancies has been a scope of controversy as the current literature is highly inconsistent in this regard. To evaluate the association between AA and hematological malignancies (HMs) and solid malignancies (SMs) using a large-scale, real-life computerized database. A cross-sectional study was conducted to compare the prevalence of HMs and SMs among patients with AA relative to age-, sex-, and ethnicity-matched control subjects.
Murad AbdelRaziq, Shareef Araidy, Imad Abu El Naaj: Postoperative Antibiotics May Be Unnecessary in Pediatric Patients Hospitalized With Minor Odontogenic Infections (J Oral Maxillofac Surg . )
Antibiotic overuse is a growing concern in health care. For pediatric odontogenic infections, the necessity of postoperative antibiotics lacks clear, evidence-based guidelines. The purpose of this study was to compare treatment outcomes between pediatric patients hospitalized with vestibular space odontogenic infections who received postoperative antibiotics and those who did not.
Raneen Abu Shqara, Maya Kaufman, Shany Or, Daniel Glikman, Lior Lowenstein, Maya Frank Wolf: The Utility of Serologic TORCH Testing During Pregnancy for Maternal-related Versus Fetal-related Indications: A Retrospective Study (Pediatr Infect Dis J .)
Clear guidelines have not been established about the utility of TORCH serology testing in women for whom TORCH infection is suspected according to clinical and laboratory manifestations during pregnancy. We aimed to compare rates of TORCH infections [specifically cytomegalovirus (CMV), Toxoplasma and rubella] in women who underwent TORCH serology testing due to maternal- versus fetal-related indications.