Recent Publications
Salim T Khoury, Amir Mari: The possible association between neurodegenerative/demyelinating neurological disorders in achalasia patients (Transl Neurosci .)
The precise pathogenesis of achalasia is still unclear. Neurodegenerative and/or demyelinating disorders (NDD) appear to share some common pathophysiological pathways described in achalasia such as inflammation, autoimmune, mitochondrial dysfunction, and neurodegeneration. Jerie et al. have published on the October issue a prospective study assessing the prevalence of several NDD in achalasia patients. In this commentary, we shed some light on the possible link between achalasia and NDD as well as comment on the study by Jerie et al.
Michael Edelstein: Health System Barriers to Child Mandatory and Optional Vaccination among Ukrainian Migrants in Poland in the Context of MMR and HPV Vaccines-A Qualitative Study (Int J Environ Res Public Health)
Background Migrants' access to healthcare services is limited. This study aimed to identify health system barriers to vaccination, specifically HPV/MMR vaccination among children in Ukrainian economic migrants (UMs).
Tali Butler: Pediatric psychiatric emergency rooms during COVID-19: a multi-center study (BMC Psychiatry .)
The COVID-19 (SARS-CoV-2) pandemic has been a major stressor for the mental health and well-being of children and adolescents. Surveys and reports from hotlines indicate a significant rise in mental health problems. As the psychiatric emergency room (ER) is a first-line free-of-charge facility for psychiatric emergencies, we expected to see a significant increase in visits, specifically of new patients suffering from anxiety, depression, or stress-related disorders.
CORRECTION/ERRATUM HERE: https://pubmed.ncbi.nlm.nih.gov/36703106/
Adi Kasem, Idan Redenski, Daniel Oren, Adeeb Zoabi, Samer Srouji, Fares Kablan: Decline in Maxillofacial Injuries during the Pandemic: The Hidden Face of COVID-19 (J Clin Med . )
Maxillofacial injuries result from a variety of daily activities. Traffic accidents, interpersonal violence, and falls represent some of the most common etiological factors behind maxillofacial fractures. During the COVID-19 outbreak, the social distancing measures imposed by healthcare authorities aimed at abolishing the spread of the viral infection. This study aimed to evaluate the effect of social distancing measures on the incidence of maxillofacial injuries.
Ohad Ronen: Emerging Concepts Impacting Head and Neck Cancer Surgery Morbidity Oncol Ther .)
All treatment modalities for head and neck cancer carry with them a risk of adverse events. Head and neck surgeons are faced with significant challenges to minimize associated morbidity and manage its sequelae. Recognizing situations in which a surgical complication is an adverse event inherent to the procedure can alleviate the psychologic impact a complication might have on the treatment team and minimize external and internal pressures. Focusing on the complications that can be effectively modified, future complications can be avoided. Also, some surgical morbidities may not be preventable, necessitating the option to reconsider whether the incidents should be labeled toxic reactions rather than a complication. This discussion highlights some of the areas in which additional research is needed to achieve the goal of minimizing the impact of surgical morbidity.
Michael Edelstein: Monitoring the COVID-19 immunisation programme through a national immunisation Management system - England's experience (Int J Med Inform . )
In England routine vaccinations are recorded in either the patients General Practice record or in series of sub-national vaccine registers that are not interoperable. During the COVID-19 pandemic it was established that COVID vaccines would need to be delivered in multiple settings where current vaccine registers do not exist. We describe how a national vaccine register was created to collect data on COVID-19 vaccines.
Khalaf Kridin, Noor Mruwat: The cardiometabolic safety of interleukin 23 versus interleukin 17 inhibitors in psoriasis: A large-scale global cohort study (J Eur Acad Dermatol Venereol . )
Robust evidence suggests that psoriasis is associated with an elevated risk of cardiovascular diseases, which embody the most common cause of morbidity and mortality among patients with psoriasis. While biologic agents undoubtedly led to a groundbreaking improvement in patient care and optimized patient outcomes, their effect on cardiovascular outcomes in psoriasis is a scope of controversy. A meta-analysis pooling 38 randomized controlled trials detected no significant influence of biologics on the incidence of major adverse cardiovascular events (MACE) in patients with psoriasis.
Offer Amir: Advanced Hemodynamic Monitoring Allows Recognition of Early Response Patterns to Diuresis in Congestive Heart Failure Patients (J Clin Med . )
There are no clear guidelines for diuretic administration in heart failure (HF), and reliable markers are needed to tailor treatment. Continuous monitoring of multiple advanced physiological parameters during diuresis may allow better differentiation of patients into subgroups according to their responses. In this study, 29 HF patients were monitored during outpatient intravenous diuresis, using a noninvasive wearable multi-parameter monitor.
Obstetrical Outcome following Diagnosis of Gestational Diabetes in the Third Trimester (>29 Weeks) versus Second Trimester (24-28 Weeks): A Retrospective Comparative Study (Am J Perinatol .)
This study aimed to compare obstetrical outcomes between women diagnosed with gestational diabetes mellitus (GDM) in the third trimester after testing negative for GDM in two-step screening in the second trimester and women diagnosed in the second trimester.
(Raneen Abu Shqara, Yara Nakhleh Francis, Shany Or, Lior Lowenstein, Maya Frank Wolf)
Jumanah Essa-Hadad, Mary Cj Rudolf, Noah Mani, Lilach Malatskey: Mapping lifestyle medicine in undergraduate medical education: a lever for enhancing the curriculum (BMC Med Educ . )
In 2017, the Bipartisan Policy Center called for inclusion of lifestyle medicine (LM) in undergraduate medical education. Recognizing the requirement that lifestyle medicine should be an integral and integrated part of the curriculum, we undertook an in-depth mapping process to determine the extent of LM teaching at our Faculty, staff perceptions and the impact on medical students.
Edo Y Birati: Left Ventricular Assist Devices: A Primer For the General Cardiologist (J Am Heart Assoc .)
Durable implantable left ventricular assist devices (LVADs) have been shown to improve survival and quality of life for patients with stage D heart failure. Even though LVADs remain underused overall, the number of patients with heart failure supported with LVADs is steadily increasing. Therefore, general cardiologists will increasingly encounter these patients. In this review, we provide an overview of the field of durable LVADs.
Ben Oren: The Effect of Preemptive Local Infiltration on Postoperative Pain Following Vaginal Hysterectomy: a Retrospective Study (Am J Perinatol .)
Investigates the effect of preemptive infiltration on postoperative pain and the use of analgesics following vaginal hysterectomy (VH).
Avi Benov: Pressure Points Technique for Traumatic Proximal Axillary Artery Hemorrhage: A Case Report (Prehosp Disaster Med . )
While the pressure points technique for proximal hemorrhage control is long known, it is not recommended in standard prehospital guidelines based on a study showing the inability to maintain occlusion for over two minutes. Main symptom: This report details a gunshot wound to the left axillary area with complete transection of the axillary artery, leading to profuse junctional hemorrhage and profound hemorrhagic shock.
Amir Bashkin, Mona Shehadeh, Lina Shbita, Kamil Namoura, Ronza Haiek, Elena Kuyantseva, Yousef Boulos, Orly Yakir, Etty Kruzel-Davila: Baseline moderate-range albuminuria is associated with protection against severe COVID-19 pneumonia (World J Diabetes .)
Diabetes mellitus is considered a leading contributor to severe coronavirus disease 2019 (COVID-19). Aim: To characterize differences between hospitalized diabetic patients with vs without COVID-19, and parameters associated with COVID-19 severity for prediction.
Khalaf Kridin: Isotretinoin and the risk of inflammatory bowel disease and irritable bowel syndrome- A large-scale global study (J Am Acad Dermatol .)
Risk of inflammatory bowel disease (IBD) under isotretinoin is a scope of a long-standing controversy. The burden of isotretinoin-related irritable bowel syndrome (IBS) has not been investigated. Objective: To evaluate the risk of Crohn`s disease (CD), ulcerative colitis (UC), and IBS in patients with acne starting isotretinoin versus oral antibiotics treatment.