Workshop: “Post-Genome analysis for musculoskeletal biology” at the Azrieli Faculty of Medicine

Organized by Prof. David Karasik and Dr. Chen Shochat-Carvalho of the Musculoskeletal Genetics Laboratory, this workshop took place at the Azrieli Faculty on July 27-29, 2022.

Based on a project funded by the Israel Science Foundation (ISF) the team introduced zebrafish as a model to validate musculoskeletal genome-wide association studies. The workshop, funded by the ISF, provided a platform for omic-centered researchers from Israel and abroad to facilitate crosstalk, establish collaboration, and validate new experimental models of musculoskeletal health. A variety of world-renown speakers provided their insights into the current and future work on the fast-growing field of the post-genomic exploration.

​The two main objectives:

• Acquire a better understanding of advantages and challenges in using the functional approaches for the bone biology in piscine and rodent models, and ultimately human cells. Specific focus is on latest advancement in imaging modalities, genetic methodologies, and nano-technology approaches. 
• Learn about the current state of knowledge and ongoing research activities in the musculoskeletal diseases, such as osteosarcopenia, falls and fracture.

The researchers hope to translate the findings of this research into novel therapeutic strategies effective for the musculoskeletal system, for preventing and treating fractures and muscle loss by targeting actionable genes.