Proton Pump Inhibitor Use May Increase the Risk of Diverticulitis but Not It's Severity among Patients with Colonic Diverticulosis: A Multicenter Study (J Clin Med .)

Colonic diverticular disease, especially diverticulitis constitutes a major cause of hospitalization and an economic burden in developed countries. Proton pump inhibitors (PPIs) are among the commonest drugs used to treat several diseases affecting the upper gastrointestinal tract. A few studies have reported that the use of Proton Pump Inhibitors PPIs caused dysbiosis. In this study, we searched for a relationship between PPI use and the onset and severity of diverticulitis in patients with colonic diverticulosis. (Wisam Sbeit, Tawfik Khoury, Anas Kadah, Waseem Asadi, Amir Shahin, Ahmad Lubany, Mohammed Safadi, Haya Haddad, Ruba Abu Ahmad, Sami Abu El Hija, Rand Abboud,  Amir Mari)