Director, The Russell Berrie Galilee Diabetes SPHERE

Prof. Naim Shehadeh

פרופ' מן המניין Professor
Director, The Russell Berrie Galilee Diabetes SPHERE
Telephone
Bar-Ilan Email
naim.shehadeh@biu.ac.il
Fields of Interest

Type 1 and 2 diabetes and its complications, prevention and treatment. Education for a healthy lifestyle and access to health services.

Research field
The Russell Berrie Galilee Diabetes SPHERE
    CV

    Prof. Shehadeh is a professor at the Faculty of Medicine at the Technion, Director of the Institute of Endocrinology, Diabetes and Metabolism at the Rambam Medical Center, Chairman of the Rambam Patents Committee, President of the Israel Diabetes Association and head of the “Galilee Diabetes SPHERE” program at the Bar Ilan University Faculty of Medicine.

    Prof. Shehadeh Naim is a graduate of the Bruce Rappaport Faculty of Medicine at the Technion. He specialized in pediatrics and Endocrinology at Rambam Hospital and completed his medical training at the University of Colorado Health Sciences Center in the USA.

    His main research topics are in the field of: pathogenesis and prevention of type 1 diabetes, the effect of orally administered insulin on the digestive system, treatment and prevention of complications in type 2 diabetes. Education for a healthy lifestyle and access to health services for disadvantaged peripheral populations.

    Prof. Shehadeh won several research awards from the Technion such as: The Hershel Rich Technion Innovation Award and The Raymond and Miriam Klein Technion Research Award.

     

    1983 – Graduated from the Faculty of Medicine, Technion, Haifa

    1988 – Completion of residency in pediatrics, Rambam Hospital

    1990 – End of residency in adult endocrinology, Rambam Hospital

    1992 – Completion of a fellowship at the Diabetes Center, Denver, Colorado, USA

    2002 – Director of the first children's department and the clinic for diabetes and a healthy lifestyle in children, Rambam Hospital

    2003 – Visiting Professor Program, Yale University, con, USA

    2006 – Clinical Associate Professor, Faculty of Medicine, Technion, Haifa

    2008 – Member of the Helsinki Committee, Rambam Hospital

    2010 – Chairman of the Patents Committee, Rambam University

    2010 – Member of the National Diabetes Council, and Chairman of the Committee for Special Populations

    2013 – Member of the steering committee of the "Otzma" project and the committee for the preparation of the national program for the prevention and treatment of diabetes - Ministry of Health

    2013 – Chairman of the Pediatric Department, Faculty of Medicine, Technion

    2015 – Director of the Diabetes School - Continuing Studies, Faculty of Medicine, Technion, Haifa

    2016 – Director of the Institute of Endocrinology, Diabetes and Metabolism, Rambam Hospital

    2016 – Center for Endocrinology and Diabetes Studies, Faculty of Medicine, Technion, Haifa

    2017 – President of the Israeli Diabetes Association

    2017 – Chairman of the Endocrine Department, Faculty of Medicine, Technion, Haifa

    2019 – Full Clinical Professor, Faculty of Medicine, Technion, Haifa

    2022 – Director of The Russell Berrie Galilee Diabetes SPHERE

    2023 – Full Professor, Azrieli Faculty of Medicine, Bar-Ilan University, Safed

    2024 Member of the Israeli National Academy of Science in Medicine, Israeli Medical Association

    Research
    • Gastrointestinal tract as a target organ of oral insulin: studies on the effect of orally administered insulin on the maturation of the GI tract.
    • Development of new infant formulas enriched with insulin for better maturation of gastrointestinal system in premature infants. A start-up company was established (Nutrinia) with great success. The new infant formula was developed, and human clinical trial trials are being carried out. Phase 1 and phase 2 trials were completed successfully, and in August 2016, phase 3 studies commenced in Europe and the USA. More than $42 million were raised as investments during the years 2014-2016.
    • Metabolic control of diabetic patients.
    • Prevention of acute and chronic diabetes complications.
    Publications

    Selected bibliography:

    Birati Y, Yefet E, Perlitz Y, Shehadeh N, Spitzer S. Cultural and Digital Health Literacy Appropriateness of App- and Web-Based Systems Designed for Pregnant Women With Gestational Diabetes Mellitus: Scoping Review. J Med Internet Res. 2022 Oct 14;24(10):e37844. doi: 10.2196/37844. PMID: 36240008

    Nakhleh A, Sakhnini R, Furman E, Shehadeh N. Cardiometabolic risk factors among children and adolescents with overweight and Class 1 obesity: A cross-sectional study. Insights from stratification of Class 1 obesity. Front Endocrinol (Lausanne). 2023 Jan 30;14:1108618. doi: 10.3389/fendo.2023.1108618. eCollection 2023.

    Nakhleh A, Spitzer S, Shehadeh N. ChatGPT’s Response to the Diabetes Knowledge Questionnaire: Implications for Diabetes Education. Diabetes Technology and Therapeutics. 2023 Aug;25(8):571-573. doi: 10.1089/dia.2023.0134.

    Nakhleh A, Goldenberg-Furmanov M, Goldstein R, Shohat M, Shehadeh N. A beneficial role of GLP-1 receptor agonist therapy in ABCC8-MODY (MODY 12). Journal of Diabetes and its Complications. 2023 Sep 1;37(9):108566.

    Nakhleh A, Othman A, Masri A, Zloczower M, Zolotov S, Shehadeh N. Clinical Outcomes of Diabetic Ketoacidosis in Type 2 Diabetes Patients with and without SGLT2 Inhibitor Treatment: A Retrospective Study. Biomedicines. 2023 Oct 1;11(10):2689.

    Tamborlane W, Shehadeh N. Unmet Needs in the Treatment of Childhood Type 2 Diabetes:  Narrative Review. Adv Ther. 2023 Nov;40(11):4711-4720. doi: 10.1007/s12325-023-02642-7.

    Shehadeh N, Barrett T, Galassetti P, Karlsson C, Monyak J, Iqbal N, Tamborlane WV. Dapagliflozin or Saxagliptin in Pediatric Type 2 Diabetes. NEJM Evid. 2023 Dec;2(12):EVIDoa2300210. doi: 10.1056/EVIDoa2300210.

    Nakhleh A, Mazareeb J, Darawshi S, Masri A, Shehadeh N. Safety and Effectiveness of Sodium-Glucose Co-transporter 2 Inhibitors on Glycemic Control in Patients with Type 2 Diabetes Mellitus Fasting during Ramadan: A Review. Clin Med Insights Endocrinol Diabetes. 2024 Mar 14;17:11795514241238058.

    Nakhleh A, Halfin E, Shehadeh N. Remission of type 2 diabetes mellitus. World J Diabetes 2024; 15(7): 1384-1389 [PMID: 39099816 DOI: 10.4239/wjd.v15.i7.1384]

    Last Updated Date : 25/09/2024